Literature Review Of Diabetes Mellitus

Literature Review Of Diabetes Mellitus-2
Selection of articles was based on titles and abstracts than on the full text. Two authors (KL and CV) extracted the following data: study design and population (observational study, quality score, definition of DM and OA and localisation of OA); exposure glycaemia (fasting blood glucose (FBG) level, mmol/L) or glycosylated haemoglobin (Hb A1c; %) or number of patients with DM; outcome (number of patients with OA); body mass index (BMI, kg/m) or number of patients with obesity as potential confounders; association measure (relative risk or OR or only conclusion on an association).Then we conversely considered OA as an exposure factor and DM as an outcome.

Selection of articles was based on titles and abstracts than on the full text. Two authors (KL and CV) extracted the following data: study design and population (observational study, quality score, definition of DM and OA and localisation of OA); exposure glycaemia (fasting blood glucose (FBG) level, mmol/L) or glycosylated haemoglobin (Hb A1c; %) or number of patients with DM; outcome (number of patients with OA); body mass index (BMI, kg/m) or number of patients with obesity as potential confounders; association measure (relative risk or OR or only conclusion on an association).Then we conversely considered OA as an exposure factor and DM as an outcome.

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We used the following key words for the Pub Med search: (“diabetes mellitus, type 2”[Me SH] OR “diabetes mellitus, type 1”[Me SH] OR “diabetes complications”[Me SH] OR “metabolic syndrome X”[Me SH] OR (“blood glucose”[Me SH] OR “blood glucose”[All Fields])) AND “osteoarthritis”[Me SH] AND (“humans”[Me SH] AND (English[lang] OR French[lang])).

Results From the 299 publications, we included 49 studies in the analysis, including 28 cross-sectional studies, 11 cohort studies and 10 case–control studies.

In all, 21, 5 and 23 articles involved patients with OA exclusively, patients with DM and the general population, respectively.

We performed a systematic review of the literature according to the Cochrane guidelines ( 24 February 2014, date last accessed).

Relevant publications were selected from three databases (Pub Med, EMBASE and the Cochrane Library) without any limitation on time (up to June 2013 and updated in January 2015).

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